What DSIP is
DSIP stands for delta sleep-inducing peptide. Its formal name is emideltide, which is the name FDA uses. It's a peptide of nine amino acids. FDA's review gives the formula of the free base as C35H48N10O15 and its molecular weight as 848.8 g/mol.
Where it stands with the FDA
DSIP isn't approved by the FDA, and the agency says it isn't a component of any FDA-approved drug. It was nominated for compounding, the nominations were withdrawn, and FDA reviewed it on its own initiative.
The review looked at opioid withdrawal and two sleep disorders, chronic insomnia and narcolepsy. It concluded that the criteria weigh against putting DSIP on the list of substances pharmacies may compound with, and it notes that the free base dissolves poorly in water.
FDA took the question to its Pharmacy Compounding Advisory Committee on July 24, 2026. Its meeting page had no minutes posted as of October 2026, so this page doesn't report a vote.
The strength in the record
FDA evaluated it as an injection under the skin at 1,000 mcg/mL, which is 1 mg/mL.
| Strength in the record | Water for a 5 mg vial | One unit holds | 10 units hold |
|---|---|---|---|
| 1,000 mcg/mL | 5 mL | 10 mcg | 100 mcg |
Add that much water to a 5 mg vial and it comes to that strength. Any other amount of water works too. It only changes how many units the same dose takes up.
Storing DSIP
FDA's review says the free base is expected to be stable stored below -20°C, and repeats a report that the lyophilized powder is stable at room temperature for three weeks. Both describe the dry powder, not a mixed vial.
There's no approved label for DSIP, so nothing official says how long a mixed vial keeps.
DSIP dosage calculator questions
How do I turn a DSIP dose into syringe units?
Divide the dose by the concentration to get millilitres, then multiply by 100. A 5 mg vial mixed with 5 mL is 1 mg/mL, so one unit on an insulin syringe holds 10 mcg and ten units hold 100 mcg.
How much bacteriostatic water goes in a 5 mg vial of DSIP?
There's no single right amount. The water only sets the concentration, and the amount of DSIP in the vial stays the same. With 5 mg, 1 mL makes 5 mg/mL, 2 mL makes 2.5 mg/mL and 3 mL makes 1.667 mg/mL. Choose the amount that puts your dose somewhere between about 10 and 40 units, where it's easiest to read.
Is DSIP approved by the FDA?
No. FDA says DSIP, which it calls emideltide, isn't a component of any FDA-approved drug. It reviewed DSIP for use in compounded drugs and concluded the criteria weigh against it, then took it to an advisory committee on July 24, 2026.
Does this page tell me how much DSIP to take?
No. There's no FDA-approved DSIP product, so there's no approved dose to point to. The dose box starts empty for that reason, and the chart only converts.
Is DSIP the same thing as emideltide?
Yes. Emideltide is the formal name and DSIP, short for delta sleep-inducing peptide, is the common one. FDA's review uses emideltide and notes the other name.
More peptide calculators by name
The same instrument, set up one peptide at a time. For any other vial, use the peptide reconstitution calculator.